Publications by Stokes, L

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Journal Articles (24)
Dhuna, K, Felgate, M, Bidula, S, Walpole, S, Bibic, L, Cromer, B, Angulo, J, Sanderson, J, Stebbing, M and Stokes, L 2019, 'Ginsenosides act as positive modulators of P2X4 receptors', Molecular Pharmacology, vol. 95, no. 2, pp. 210-221. 10   3 9
De Luca, S, Ziko, I, Dhuna, K, Sominsky, L, Tolcos, M, Stokes, L and Spencer, S 2017, 'Neonatal overfeeding by small-litter rearing sensitises hippocampal microglial responses to immune challenge: Reversal with neonatal repeated injections of saline or minocycline', Journal of Neuroendocrinology, vol. 29, no. 11, pp. 1-14. 11   4 0
Stokes, L, Layhadi, J, Bibic, L, Dhuna, K and Fountain, S 2017, 'P2X4 receptor function in the nervous system and current breakthroughs in pharmacology', Frontiers in Pharmacology, vol. 8, 291, pp. 1-15. 72 45 37 Cited 2 times in Scopus2 2
Gilbert, D, Stebbing, M, Kuenzel, K, Murphy, R, Zacharewicz, E, Buttgereit, A, Stokes, L, Adams, D and Friedrich, O 2016, 'Store-Operated Ca2+ Entry (SOCE) and Purinergic Receptor-Mediated Ca2+ Homeostasis in Murine bv2 Microglia Cells: Early Cellular Responses to ATP-Mediated Microglia Activation', Frontiers in Molecular Neuroscience, vol. 9, no. OCT2016, 111, pp. 1-15. 148 41 7 Cited 1 times in Scopus1 2
Stokes, L, Spencer, S and Jenkins, T 2015, 'Understanding the role of P2X7 in affective disorders - are glial cells the major players?', Frontiers in Cellular Neuroscience, vol. 9, 258, pp. 1-6. 116 37 30 Cited 17 times in Scopus17 2
Helliwell, R, Shiouk Huey Ong, C, Dhuna, K, Molero - Navajas, J, Ye, J, Xue, C and Stokes, L 2015, 'Selected ginsenosides of the protopanaxdiol series are novel positive allosteric modulators of P2X7 receptors', British Journal of Pharmacology, vol. 172, no. 13, pp. 3326-3340. 76   18 Cited 9 times in Scopus9 2
Higgins, K, Kovacevic, W and Stokes, L 2014, 'Nucleotides regulate secretion of the inflammatory Chemokine CCL2 from human macrophages and monocytes', Mediators of Inflammation, vol. 48, 293925, pp. 1-13. 92   6 1
Spildrejorde, M, Bartlett, R, Stokes, L, Jalilian, I, Peranec, M, Sluyter, V, Curtis, B, Skarratt, K, Skora, A, Bakhsh, T, Seavers, A, McArthur, J, Dowton, M and Sluyter, R 2014, 'R270C polymorphism leads to loss of function of the canine P2X7 receptor', Physiological Genomics, vol. 46, no. 14, pp. 512-522. 74   7 Cited 7 times in Scopus7 0
Bartlett, R, Stokes, L and Sluyter, R 2014, 'The p2x7 receptor channel: Recent developments and the use of p2x7 antagonists in models of disease', Pharmacological Reviews, vol. 66, no. 3, pp. 638-675. 111   200 Cited 122 times in Scopus122 5
Ziko, I, De Luca, S, Dinan, T, Barwood, J, Sominsky, L, Cai, G, Kenny, R, Stokes, L, Jenkins, T and Spencer, S 2014, 'Neonatal overfeeding alters hypothalamic microglial profiles and central responses to immune challenge long-term', Brain, Behavior, and Immunity, vol. 41, pp. 32-43. 244   38 0 0
Bhaskaracharya, A, Dao-Ung, P, Jalilian, I, Spildrejorde, M, Skarratt, K, Fuller, S, Sluyter, R and Stokes, L 2014, 'Probenecid blocks human P2X7 receptor-induced dye uptake via a pannexin-1 independent mechanism', PLoS ONE, vol. 9, no. 3, e93058, pp. 1-8. 26   42 Cited 28 times in Scopus28 2
Lester, S, Stokes, L, Skarratt, K, Gu, B, Sivils, K, Lessard, C, Wiley, J and Rischmueller, M 2013, 'Epistasis with HLA DR3 implicates the P2X7 receptor in the pathogenesis of primary Sjögren's syndrome', Arthritis Research and Therapy, vol. 15, no. 4, pp. 1-10. 100 102 14 Cited 12 times in Scopus12 1
Pupovac, A, Stokes, L and Sluyter, R 2013, 'CAY10593 inhibits the human P2X7 receptor independently of phospholipase D1 stimulation', Purinergic Signalling, vol. 9, no. 4, pp. 609-619. 157   9 Cited 8 times in Scopus8 0
Gartland, A, Skarratt, K, Hocking, L, Parsons, C, Stokes, L, Jorgensen, N, Fraser, W, Reid, D, Gallagher, J and Wiley, J 2012, 'Polymorphisms in the P2X7 receptor gene are associated with low lumbar spine bone mineral density and accelerated bone loss in post-menopausal women', European Journal of Human Genetics, vol. 20, no. 5, pp. 559-564. 93 185 46 Cited 36 times in Scopus36 7
Jorgensen, N, Husted, L, Skarratt, K, Stokes, L, Tofteng, C, Kvist, T, Jensen, J, Eiken, P, Brixen, K, Fuller, S, Clifton-Bligh, R, Gartland, A, Schwarz, P, Langdahl, B and Wiley, J 2012, 'Single nucleotide polymorphisms in the P2X7 receptor gene are associated with post-menopausal bone loss and vertebral fractures', European Journal of Human Genetics, vol. 20, no. 6, pp. 675-681. 66   46 Cited 37 times in Scopus37 1
Sluyter, R and Stokes, L 2011, 'Significance of P2X7 receptor variants to human health and disease', Recent Patents on DNA and Gene Sequences, vol. 5, no. 1, pp. 41-54. 18   Cited 53 times in Scopus53
Wiley, J, Sluyter, R, Gu, B, Stokes, L and Fuller, S 2011, 'The human P2X7 receptor and its role in innate immunity', Tissue Antigens, vol. 78, no. 5, pp. 321-332. 70   119 Cited 96 times in Scopus96 1
Stokes, L, Fuller, S, Sluyter, R, Skarratt, K, Gu, B and Wiley, J 2010, 'Two haplotypes of the P2X7 receptor containing the Ala-348 to Thr polymorphism exhibit a gain-of-function effect and enhanced interleukin-1ß secretion', The FASEB Journal, vol. 24, no. 8, pp. 2916-2927. 93   100 Cited 90 times in Scopus90 0
Fuller, S, Stokes, L, Skarratt, K, Gu, B and Wiley, J 2009, 'Genetics of the P2X7 receptor and human disease', Purinergic Signalling, vol. 5, no. 2, pp. 257-262. 63   83 Cited 71 times in Scopus71 0
Gu, B, Rathsam, C, Stokes, L, McGeachie, A and Wiley, J 2009, 'Extracellular ATP dissociates nonmuscle myosin from P2X7 complex: This dissociation regulates P2X7 pore formation', American Journal of Physiology: Cell Physiology, vol. 297, no. 2, pp. 430-439. 116   52 Cited 45 times in Scopus45 0
Stokes, L and Surprenant, A 2009, 'Dynamic regulation of P2X4 receptor in alveolar macrophages by phagocytosis and classical activation', European Journal of Immunology, vol. 39, no. 4, pp. 986-995. 154   32 Cited 32 times in Scopus32 1
Shemon, A, Sluyter, R, Stokes, L, Manley, P and Wiley, J 2008, 'Inhibition of the human P2X7 receptor by a novel protein tyrosine kinase antagonist', Biochemical and Biophysical Research Communications, vol. 365, no. 3, pp. 515-520. 50   11 Cited 12 times in Scopus12 0
Vaughan, K, Stokes, L, Prince, L, Marriott, H, Meis, S, Kassack, M, Bingle, C, Sabroe, I, Surprenant, A and Whyte, M 2007, 'Inhibition of neutrophil apoptosis by ATP is mediated by the P2Y11 receptor', Journal of Immunology, vol. 179, no. 12, pp. 8544-8553. 89   71 Cited 63 times in Scopus63
Stokes, L, Jiang, L, Alcaraz, L, Bent, J, Bowers, K, Fagura, M, Furber, M, Mortimore, M, Lawson, M, Theaker, J, Laurent, C, Braddock, M and Surprenant, A 2006, 'Characterization of a selective and potent antagonist of human P2X(7) receptors, AZ11645373', British Journal of Pharmacology, vol. 149, no. 7, pp. 880-887. 94   94
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