Quantitation of renal function based on two-compartmental modeling of renal pelvis

Loh, K, Ng, D, Ghista, D and Rudolph, H 2005, 'Quantitation of renal function based on two-compartmental modeling of renal pelvis', in T. Tamura and H. L. Galiana (ed.) Proceedings of the 27th Annual IEEE International Conference of the Engineering in Medicine and Biology Society, Shanghai, 17-18 January 2006.


Document type: Conference Paper
Collection: Conference Papers

Title Quantitation of renal function based on two-compartmental modeling of renal pelvis
Author(s) Loh, K
Ng, D
Ghista, D
Rudolph, H
Year 2005
Conference name International Conference of the Engineering in Medicine and Biology Society
Conference location Shanghai
Conference dates 17-18 January 2006
Proceedings title Proceedings of the 27th Annual IEEE International Conference of the Engineering in Medicine and Biology Society
Editor(s) T. Tamura
H. L. Galiana
Publisher IEEE
Place of publication Shanghai
Abstract The primary functions of the kidney are: (i) to get rid of the body waste materials that are either ingested or produced by metabolism, and (ii) to control the volume and composition of the body fluids. Herein, we provide a noninvasive methodology to assess physiological function of the kidneys. For this purpose, we analyze the renograms with 2-compartmental modelling of the kidney-renal outflow system, and therefrom compute the amount of flow of renal radionuclide into and out of the renal pelvis compartment. The derived information of uptake (k/A) and washout (e(beta/2V2)t sinhAt) rates can be of considerable use. The paper provides a number of case studies for the verification of the derived system governing equations against clinical renograms
Subjects Biomedical Engineering not elsewhere classified
Keyword(s) renal outflow obstruction
renal function
glomerular filtration rate
DOI - identifier 10.1109/IEMBS.2005.1616937
Copyright notice © 2005 IEEE.
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