Molecular mechanisms in Schwann cell survival and death during peripheral nerve development, injury and disease

Boyle, K, Azari, M, Profyris, C and Petratos, S 2005, 'Molecular mechanisms in Schwann cell survival and death during peripheral nerve development, injury and disease', Neurotoxicity Research, vol. 7, no. 12, pp. 151-167.


Document type: Journal Article
Collection: Journal Articles

Title Molecular mechanisms in Schwann cell survival and death during peripheral nerve development, injury and disease
Author(s) Boyle, K
Azari, M
Profyris, C
Petratos, S
Year 2005
Journal name Neurotoxicity Research
Volume number 7
Issue number 12
Start page 151
End page 167
Total pages 17
Publisher Springer New York LLC
Abstract The mechanisms determining the fate of Schwann cells during disease and injury of the adult mammalian peripheral nervous system (PNS) are becoming defined by current advances in molecular neurobiology. It is now apparent that the molecular pathways which regulate the production of the mature myelinating Schwann cell during development may also apply to degenerative and regenerative mechanisms following PNS disease
Subject Neurology and Neuromuscular Diseases
Keyword(s) Schwann cell death
Schwann cell development
Inflammatory demyelinating polyneuropathy
Wallerian degeneration
Tumour necrosis factor-
Neurotrophins
-neuregulin
Low affinity neurotrophin receptor
Matrix metalloproteinases
DOI - identifier 10.1007/BF03033784
Copyright notice © 2005 FP Graham Publishing
ISSN 1029-8428
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