Design and simulation of an interdigital-chaotic advection micromixer for lab-on-a-chip applications

Khoshmanesh, K, Kouzani, A, Nahavandi, S, Baratchi, S and Kanwar, J 2008, 'Design and simulation of an interdigital-chaotic advection micromixer for lab-on-a-chip applications', in Colin, Stephane, Luca Morini, Gian (ed.) MicroFlu 2008 : Proceedings of the 1st European Conference on Microfluidics, Bologna, Italy, 10th-12th December 2008, pp. 1-9.


Document type: Conference Paper
Collection: Conference Papers

Title Design and simulation of an interdigital-chaotic advection micromixer for lab-on-a-chip applications
Author(s) Khoshmanesh, K
Kouzani, A
Nahavandi, S
Baratchi, S
Kanwar, J
Year 2008
Conference name European Conference on Microfluidics
Conference location Bologna, Italy
Conference dates 10th-12th December 2008
Proceedings title MicroFlu 2008 : Proceedings of the 1st European Conference on Microfluidics
Editor(s) Colin, Stephane, Luca Morini, Gian
Publisher Societe Hydrotechnique de France SHF
Place of publication Paris, France
Start page 1
End page 9
Total pages 9
Abstract This paper presents the design and simulation of a novel passive micromixer The micromixer consists of two inlet tanks, one mixing channel and two outlet channels. In order to maximise the mixing efficiency, the following considerations are made : (i) The inlet tanks are followed by a series of microchannels, in which the flow is split. The microchannels are arranged in an interdigital manner to maximise the contact area between the two flows. (ii) The microchannels attached to the lower inlet tank have an upward slope while those attached to the upper tank have a downward slope. The higher-density flow is fed to the lower inlet tank and gets an upward velocity before entering the mixing channel. (iii) Two triangular barriers are placed within the mixing channel to impose chaotic advection and perturb the less-mixed flow along the top and bottom surfaces of the channel. (ii) Finally, two outlet channels are incorporated to discard the less-mixed flow Three-dimensional simulations are carried out to evaluate the performance of the micromixer Simulations are performed in the absence and presence of the gravitational force to analyse the influence of gravity on the micromixer. Mixing efficiencies of greater than 92% are achieved using water and a low-density biological solvent as the mixing fluids
Subjects Microelectromechanical Systems (MEMS)
DOI - identifier 10.1051/lhb/2009088
Copyright notice © 2008 Societe Hydrotechnique de France SHF
ISBN 9782906831766
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