Aetiology and pathogenesis of chronic leukaemias

Kwa, F and Karagiannis, T 2012, 'Aetiology and pathogenesis of chronic leukaemias' in Tom C. Karagiannis and Faith A.A Kwa (ed.) Epigenomic Medicine II - Haematalogical Malignancies, Transworld Research Network, Kerala, India, pp. 21-29.


Document type: Book Chapter
Collection: Book Chapters

Title Aetiology and pathogenesis of chronic leukaemias
Author(s) Kwa, F
Karagiannis, T
Year 2012
Title of book Epigenomic Medicine II - Haematalogical Malignancies
Publisher Transworld Research Network
Place of publication Kerala, India
Editor(s) Tom C. Karagiannis and Faith A.A Kwa
Start page 21
End page 29
Subjects Haematological Tumours
Summary Chronic myelogenous leukemia is relatively rare type of leukaemia which is characterized by the BCR-ABL gene and the Philadelphia chromosome. In contrast, chronic lymphocytic leukaemia (CLL) is relatively common and is characterised by the clonal expansion of mature CD5+/CD 19+ B lymphocytes. The aim of this chapter is to describe the pathogenesis of chronic leukaemias. Specifically, the molecular basis of chronic myelogenous and chronic lyphocytic leukaemias is considered.
Copyright notice © Transworld Research Network 2012
ISBN 9788178955773
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