Protein response to electric field stress

Budi, A, Legge, F, Treutlein, H and Yarovsky, I 2005, 'Protein response to electric field stress', in Proceedings of the 16th National Congress 2005 Australian Institute of Physics - Physics for the Nation, Canberra, Australia, 30 January - 4 February 2005.


Document type: Conference Paper
Collection: Conference Papers

Title Protein response to electric field stress
Author(s) Budi, A
Legge, F
Treutlein, H
Yarovsky, I
Year 2005
Conference name 16th National Congress 2005 Australian Institute of Physics
Conference location Canberra, Australia
Conference dates 30 January - 4 February 2005
Proceedings title Proceedings of the 16th National Congress 2005 Australian Institute of Physics - Physics for the Nation
Publisher Australian Institute of Physics
Place of publication Canberra, Australia
Abstract Proteins can change conformation under stress, which can lead to disruption of their biological function and result in a number of diseases[1]. In an effort to understand the effect of external stresses on protein conformation, we have performed long term molecular dynamics simulations of insulin chain ß in several different environments. The conformational behaviour of the protein under thermal and electric field stresses was compared to the reference system under ambient conditions. We found the system under electric field stress to behave similarly to the system under thermal stress, both adopting conformations rarely seen under ambient conditions.
Subjects Condensed Matter Physics not elsewhere classified
Copyright notice © 2005 Australian Institute of Physics
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