At a glance: cellular biology for engineers

Khoshmanesh, K, Kouzani, A, Nahavandi, S, Baratchi, S and Kanwar, J 2008, 'At a glance: cellular biology for engineers', Computational Biology and Chemistry, vol. 32, no. 5, pp. 315-331.


Document type: Journal Article
Collection: Journal Articles

Title At a glance: cellular biology for engineers
Author(s) Khoshmanesh, K
Kouzani, A
Nahavandi, S
Baratchi, S
Kanwar, J
Year 2008
Journal name Computational Biology and Chemistry
Volume number 32
Issue number 5
Start page 315
End page 331
Total pages 17
Publisher Elsevier Ltd
Abstract Engineering contributions have played an important role in the rise and evolution of cellular biology. Engineering technologies have helped biologists to explore the living organisms at cellular and molecular levels, and have created new opportunities to tackle the unsolved biological problems. There is now a growing demand to further expand the role of engineering in cellular biology research. For an engineer to play an effective role in cellular biology, the first essential step is to understand the cells and their components. However, the stumbling block of this step is to comprehend the information given in the cellular biology literature because it best suits the readers with a biological background. This paper aims to overcome this bottleneck by describing the human cell components as micro-plants that form cells as micro-bio-factories. This concept can accelerate the engineers' comprehension of the subject. In this paper, first the structure and function of different cell components are described. In addition, the engineering attempts to mimic various cell components through numerical modelling or physical implementation are highlighted. Next, the interaction of different cell components that facilitate complicated chemical processes, such as energy generation and protein synthesis, are described. These complex interactions are translated into simple flow diagrams, generally used by engineers to represent multi-component processes
Subject Biological Sciences not elsewhere classified
Keyword(s) Cell organelles
Cellular biology
Energy generation
Micro-bio-factory
Protein synthesis
DOI - identifier 10.1016/j.compbiolchem.2008.07.010
Copyright notice © 2008 Elsevier Ltd. All rights reserved.
ISSN 1476-9271
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