Possibility to interfere with malaria parasite activity using specific electromagnetic frequencies

Cosic, I, Caceres, J and Cosic, D 2015, 'Possibility to interfere with malaria parasite activity using specific electromagnetic frequencies', EPJ Nonlinear Biomedical Physics, vol. 3, no. 11, pp. 1-11.


Document type: Journal Article
Collection: Journal Articles

Title Possibility to interfere with malaria parasite activity using specific electromagnetic frequencies
Author(s) Cosic, I
Caceres, J
Cosic, D
Year 2015
Journal name EPJ Nonlinear Biomedical Physics
Volume number 3
Issue number 11
Start page 1
End page 11
Total pages 11
Publisher SpringerOpen
Abstract The absence of clear breakthrough in malaria combat could support the need for different ways of tackling the disease that are substantiated by conceptually new bases. The main idea of this research is to analyze possibility to interfere with malaria parasite activity using specific resonant electromagnetic frequencies. Although the idea to combat malaria infection with electromagnetic frequencies is not new, we will here present unique approach, so called Resonant Recognition Model (RRM) to specifically identify electromagnetic frequencies mostly important for interference with malaria infection. The RRM is calculating periodicities (frequencies) in distribution of free electron energies along protein sequence which are relevant for protein function/interaction. When charge transfer through protein backbone is considered then it can produce electromagnetic radiation of specific frequency depending on charge velocity. Ten groups of proteins relevant for Plasmodium interactions were analyzed. Each of ten groups of proteins have at least one significant characteristic frequency peak at one of the following RRM frequencies: f = 0.002, f = 0.11 or f = 0.34. This suggests that the diversity of proteins participating in Plasmodium invasion could be represented with only three RRM frequencies. Depending on the charge transfer mechanism (velocity) along the protein, different electromagnetic resonant frequencies are expected. Based on presented results, we suggest that the RRM frequency of f = 0.002 (related to 2-5THz), to be regarded as crucial for Plasmodium infectivity and possibly for interfering with invasion process. Although this far infrared electromagnetic frequency cannot penetrate human body more than down to 4 cm, such radiation can be of great help in combating Plasmodium, since a sizeable part of parasite remain in the skin for hours after the mosquito bite. In addition the specific RRM frequency is capable to resonantly initiate a whole cascade of protein-protein (DNA, RNA) interactions directed to the specific biological activity which could contra-act Plasmodium infection.
Subject Biomedical Engineering not elsewhere classified
Keyword(s) Resonant Recognition Model
Malaria
Plasmodium
Macromolecular Interaction
Electromagnetic Radiation
DOI - identifier 10.1140/epjnbp/s40366-015-0025-1
Copyright notice © 2015 Cosic et al. Open Access This article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made.
ISSN 2195-0008
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