Graphene-gold nanoparticles hybrid-synthesis, functionalization, and application in a electrochemical and surface-enhanced raman scattering biosensor

Khalil, I, Julkapli, N, Yehye, W, Basirun, W and Bhargava, S 2016, 'Graphene-gold nanoparticles hybrid-synthesis, functionalization, and application in a electrochemical and surface-enhanced raman scattering biosensor', Materials, vol. 9, no. 6, pp. 1-38.


Document type: Journal Article
Collection: Journal Articles

Attached Files
Name Description MIMEType Size
n2006062397.pdf Published Version application/pdf 2.53MB
Title Graphene-gold nanoparticles hybrid-synthesis, functionalization, and application in a electrochemical and surface-enhanced raman scattering biosensor
Author(s) Khalil, I
Julkapli, N
Yehye, W
Basirun, W
Bhargava, S
Year 2016
Journal name Materials
Volume number 9
Issue number 6
Start page 1
End page 38
Total pages 38
Publisher MDPI AG
Abstract Graphene is a single-atom-thick two-dimensional carbon nanosheet with outstanding chemical, electrical, material, optical, and physical properties due to its large surface area, high electron mobility, thermal conductivity, and stability. These extraordinary features of graphene make it a key component for different applications in the biosensing and imaging arena. However, the use of graphene alone is correlated with certain limitations, such as irreversible self-agglomerations, less colloidal stability, poor reliability/repeatability, and non-specificity. The addition of gold nanostructures (AuNS) with graphene produces the graphene-AuNS hybrid nanocomposite which minimizes the limitations as well as providing additional synergistic properties, that is, higher effective surface area, catalytic activity, electrical conductivity, water solubility, and biocompatibility. This review focuses on the fundamental features of graphene, the multidimensional synthesis, and multipurpose applications of graphene-Au nanocomposites. The paper highlights the graphene-gold nanoparticle (AuNP) as the platform substrate for the fabrication of electrochemical and surface-enhanced Raman scattering (SERS)-based biosensors in diverse applications as well as SERS-directed bio-imaging, which is considered as an emerging sector for monitoring stem cell differentiation, and detection and treatment of cancer.
Subject Sensor Technology (Chemical aspects)
Keyword(s) Graphene
Graphene-gold nanoparticle
Electrochemical biosensor
SERS biosensor
Bioimaging
DOI - identifier 10.3390/ma9060406
Copyright notice © 2016 by the authors; licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC-BY) license (http://creativecommons.org/licenses/by/4.0/).
ISSN 1996-1944
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 54 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 17 times in Scopus Article | Citations
Altmetric details:
Access Statistics: 65 Abstract Views, 5 File Downloads  -  Detailed Statistics
Created: Wed, 08 Jun 2016, 08:47:00 EST by Catalyst Administrator
© 2014 RMIT Research Repository • Powered by Fez SoftwareContact us