Au nanospikes as a non-enzymatic glucose sensor: Exploring morphological changes with the elaborated chronoamperometric method

Coyle, V, Sabri, Y, Bhargava, S and Kandjani, A 2016, 'Au nanospikes as a non-enzymatic glucose sensor: Exploring morphological changes with the elaborated chronoamperometric method', Electroanalysis, vol. 29, no. 1, pp. 294-304.


Document type: Journal Article
Collection: Journal Articles

Title Au nanospikes as a non-enzymatic glucose sensor: Exploring morphological changes with the elaborated chronoamperometric method
Author(s) Coyle, V
Sabri, Y
Bhargava, S
Kandjani, A
Year 2016
Journal name Electroanalysis
Volume number 29
Issue number 1
Start page 294
End page 304
Total pages 10
Publisher Wiley - VCH Verlag GmbH and Co. KGaA
Abstract There is a continuous increasing demand for more sensitive and selective non-enzymatic glucose sensor applications ranging from medical diagnostics to food quality assurance. Here, we deposited gold nanostructures (referred to as Au nanospikes) on Au thin-film substrates under different electrodeposition conditions in order to determine the optimal growth parameters to obtain an enhanced glucose sensor. A modified chronoamperometric technique was employed to determine the glucose electrooxidation and sensing capabilities of the developed Au nanospikes toward 20muM-10mM glucose concentrations. The sensing method used here allowed for accurate determination of glucose concentrations whilst providing reproducible and stable response profiles. The sensor produced a low detection limit of 20muM, a very high sensitivity of 201muAmM-1cm-2 compared to 16.19muAmM-1cm-2 for the unmodified Au substrate. The sensor also showed good selectivity when analysed against common physiological contaminants that usually interfere with conventional sensors.
Subject Synthesis of Materials
Sensor Technology (Chemical aspects)
Electrochemistry
Keyword(s) Au nanospike
Elaborated chronoamperometry
Electrochemical sensing
Glucose sensing
Non-enzymatic glucose sensor
DOI - identifier 10.1002/elan.201600138
Copyright notice © 2016 Wiley-VCH Verlag GmbH and Co. KGaA, Weinheim
ISSN 1040-0397
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