Assessment of skin photoaging with reflectance confocal microscopy

Haytoglu, N, Gurel, M, Erdemir, A, Falay, T, Dolgun, N and Haytoglu, T 2014, 'Assessment of skin photoaging with reflectance confocal microscopy', Skin Research and Technology, vol. 20, pp. 363-372.


Document type: Journal Article
Collection: Journal Articles

Title Assessment of skin photoaging with reflectance confocal microscopy
Author(s) Haytoglu, N
Gurel, M
Erdemir, A
Falay, T
Dolgun, N
Haytoglu, T
Year 2014
Journal name Skin Research and Technology
Volume number 20
Start page 363
End page 372
Total pages 10
Publisher Wiley-Blackwell Publishing
Abstract Background/Purpose: Increased interest in antiaging methods, mandates a development of reliable noninvasive technique to assess skin aging. In this study, we aimed to determine the effects of photoaging at histopathologic resolution by means of reflectance confocal microscopy. Method: The sun-exposed malar area, the anterior aspect of ear lobule, and the sun-protected posterior aspect of ear lobule had been evaluated in 120 volunteers from different age groups over 10 previously reported and new confocal parameters for skin aging. Result: The sun-exposed areas revealed more frequent irregular honeycomb pattern, polycylic papillary contours, coarse collagen, huddled collagen, curled bright structures with higher epidermal thickness, and furrow depth values. However, the incidence of thin reticulated collagen and the number of dermal papillae were statistically higher on the sun-protected posterior aspect of ear lobule. Conclusion: Reflectance confocal microscopy is a reliable diagnostic technique for evaluation of skin photoaging with objective criteria. With the new emerging compact models it is possible to scan even the least accessible body parts with no discomfort to the patient, which offers the possibility to assess the effect of antiaging applications and to identify early signs of solar damage in cosmetically sensitive areas.
Subject Dermatology
Applied Statistics
Keyword(s) skin aging
reflectance confocal microscopy
photoaging
noninvasive imaging
collagen changes
elastosis
DOI - identifier 10.1111/srt.12127
Copyright notice © 2014 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd.
ISSN 0909-752X
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