Dielectrophoresis-based microfluidic platforms for cancer diagnostics

Chan, J, Kayani, A, Ali, M, Kok, C, Majlis, B, Hoe, S, Marzuki, M, Khoo, A, Ostrikov, K, Rahman, M and Sriram, S 2018, 'Dielectrophoresis-based microfluidic platforms for cancer diagnostics', Biomicrofluidics, vol. 12, no. 1, pp. 1-21.

Document type: Journal Article
Collection: Journal Articles

Title Dielectrophoresis-based microfluidic platforms for cancer diagnostics
Author(s) Chan, J
Kayani, A
Ali, M
Kok, C
Majlis, B
Hoe, S
Marzuki, M
Khoo, A
Ostrikov, K
Rahman, M
Sriram, S
Year 2018
Journal name Biomicrofluidics
Volume number 12
Issue number 1
Start page 1
End page 21
Total pages 21
Publisher A I P Publishing LLC
Abstract The recent advancement of dielectrophoresis (DEP)-enabled microfluidic platforms is opening new opportunities for potential use in cancer disease diagnostics. DEP is advantageous because of its specificity, low cost, small sample volume requirement, and tuneable property for microfluidic platforms. These intrinsic advantages have made it especially suitable for developing microfluidic cancer diagnostic platforms. This review focuses on a comprehensive analysis of the recent developments of DEP enabled microfluidic platforms sorted according to the target cancer cell. Each study is critically analyzed, and the features of each platform, the performance, added functionality for clinical use, and the types of samples, used are discussed. We address the novelty of the techniques, strategies, and design configuration used in improving on existing technologies or previous studies. A summary of comparing the developmental extent of each study is made, and we conclude with a treatment of future trends and a brief summary.
Subject Microelectronics and Integrated Circuits
Functional Materials
DOI - identifier 10.1063/1.5010158
ISSN 1932-1058
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