Development of functionalized mesoporous silica for adsorption and separation of dairy proteins

Sarvi, M, Bee, T, Gooi, C, Woonton, B, Gee, M and O'Connor, A 2014, 'Development of functionalized mesoporous silica for adsorption and separation of dairy proteins', Chemical Engineering Journal, vol. 235, pp. 244-251.


Document type: Journal Article
Collection: Journal Articles

Title Development of functionalized mesoporous silica for adsorption and separation of dairy proteins
Author(s) Sarvi, M
Bee, T
Gooi, C
Woonton, B
Gee, M
O'Connor, A
Year 2014
Journal name Chemical Engineering Journal
Volume number 235
Start page 244
End page 251
Total pages 8
Publisher Elsevier BV
Abstract A class of mesoporous silica material, FDU-12, was synthesized with different pore sizes and amine functionalized to determine its potential to differentially adsorb and separate dairy proteins. The adsorption behavior of the dairy proteins α-lactalbumin and β-lactoglobulin on the amino surface functionalised and unfunctionalised material was examined. It was shown that the pore size of unfunctionalised FDU-12 is an important factor in the protein adsorption capacity. Amine functionalization of FDU-12 significantly increased protein adsorption for larger pore size materials, with a marked difference in the rate of uptake between the two proteins. The kinetics of adsorption were investigated as a function of temperature and were modeled using pseudo second order kinetics and an intraparticle diffusion model, showing that intraparticle protein diffusion can be rate limiting. These results indicate that functionalised FDU-12 has potential for the selective separation of proteins with similar size and isoelectric point, under dynamic processing conditions. © 2013.
Subject Materials Engineering not elsewhere classified
Keyword(s) α-Lactalbumin
β
-Lactoglobulin
FDU-12
Mesoporous silica
Protein separation
DOI - identifier 10.1016/j.cej.2013.09.036
ISSN 1385-8947
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