Dynamic and responsive growth factor delivery from electrospun and hydrogel tissue engineering materials

Bruggeman, K, Williams, R and Nisbet, D 2017, 'Dynamic and responsive growth factor delivery from electrospun and hydrogel tissue engineering materials', Advanced Healthcare Materials, vol. 7, no. 1, pp. 1-14.


Document type: Journal Article
Collection: Journal Articles

Title Dynamic and responsive growth factor delivery from electrospun and hydrogel tissue engineering materials
Author(s) Bruggeman, K
Williams, R
Nisbet, D
Year 2017
Journal name Advanced Healthcare Materials
Volume number 7
Issue number 1
Start page 1
End page 14
Total pages 14
Publisher Wiley
Abstract Tissue engineering scaffolds are designed to mimic physical, chemical, and biological features of the extracellular matrix, thereby providing a constant support that is crucial to improved regenerative medicine outcomes. Beyond mechanical and structural support, the next generation of these materials must also consider the more dynamic presentation and delivery of drugs or growth factors to guide new and regenerating tissue development. These two aspects are explored expansively separately, but they must interact synergistically to achieve optimal regeneration. This review explores common tissue engineering materials types, electrospun polymers and hydrogels, and strategies used for incorporating drug delivery systems into these scaffolds
Subject Biomaterials
Keyword(s) drug delivery
electrospinning
hydrogel
regenerative medicine
tissue engineering
DOI - identifier 10.1002/adhm.201700836
Copyright notice © 2017 Wiley - VCH Verlag GmbH and Co. KGaA Weinheim
ISSN 2192-2659
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