The emerging role of nanomaterials in immunological sensing - a brief review

Corrie, S and Plebanski, M 2018, 'The emerging role of nanomaterials in immunological sensing - a brief review', Molecular Immunology, vol. 98, pp. 28-35.


Document type: Journal Article
Collection: Journal Articles

Title The emerging role of nanomaterials in immunological sensing - a brief review
Author(s) Corrie, S
Plebanski, M
Year 2018
Journal name Molecular Immunology
Volume number 98
Start page 28
End page 35
Total pages 8
Publisher Elsevier
Abstract Nanomaterials are beginning to play an important role in the next generation of immunological assays and biosensors, with potential impacts both in research and clinical practice. In this brief review, we highlight two areas in which nanomaterials are already making new and important contributions in the past 5-10 years: firstly, in the improvement of assay and biosensor sensitivity for detection of low abundance proteins of immunological significance, and secondly, in the real-time and continuous monitoring of protein secretion from arrays of individual cells. We finish by challenging the immunology/sensing communities to work together to develop nanomaterials that can provide real-time, continuous, and sensitive molecular readouts in vivo, a lofty goal that will require significant collaborative effort.
Subject Immunology not elsewhere classified
Keyword(s) Cell array
Cytokine
Nanomaterials
Plasmonic
Sensitivity
DOI - identifier 10.1016/j.molimm.2017.12.017
Copyright notice © 2018 Elsevier Ltd. All rights reserved.
ISSN 0161-5890
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