Perspective: Biomedical sensing and imaging with optical fibers-Innovation through convergence of science disciplines

Li, J, Ebendorff-Heidepriem, H, Gibson, B, Greentree, A, Hutchinson, M, Jia, P, Kostecki, R, Liu, G, Orth, A, Ploschner, M, Schartner, E, Warren-Smith, S, Zhang, K, Tsiminis, G and Goldys, E 2018, 'Perspective: Biomedical sensing and imaging with optical fibers-Innovation through convergence of science disciplines', APL Photonics, vol. 3, no. 10, pp. 1-20.


Document type: Journal Article
Collection: Journal Articles

Title Perspective: Biomedical sensing and imaging with optical fibers-Innovation through convergence of science disciplines
Author(s) Li, J
Ebendorff-Heidepriem, H
Gibson, B
Greentree, A
Hutchinson, M
Jia, P
Kostecki, R
Liu, G
Orth, A
Ploschner, M
Schartner, E
Warren-Smith, S
Zhang, K
Tsiminis, G
Goldys, E
Year 2018
Journal name APL Photonics
Volume number 3
Issue number 10
Start page 1
End page 20
Total pages 20
Publisher American Institute of Physics
Abstract The probing of physiological processes in living organisms is a grand challenge that requires bespoke analytical tools. Optical fiber probes offer a minimally invasive approach to report physiological signals from specific locations inside the body. This perspective article discusses a wide range of such fiber probes developed at the Australian Research Council Centre of Excellence for Nanoscale BioPhotonics. Our fiber platforms use a range of sensing modalities, including embedded nanodiamonds for magnetometry, interferometric fiber cavities for refractive index sensing, and tailored metal coatings for surface plasmon resonance sensing. Other fiber probes exploit molecularly sensitive Raman scattering or fluorescence where optical fibers have been combined with chemical and immunosensors. Fiber imaging probes based on interferometry and computational imaging are also discussed as emerging in vivo diagnostic devices. We provide examples to illustrate how the convergence of multiple scientific disciplines generates opportunities for the fiber probes to address key challenges in real-time in vivo diagnostics. These future fiber probes will enable the asking and answering of scientific questions that were never possible before.
Subject Photonics, Optoelectronics and Optical Communications
DOI - identifier 10.1063/1.5040861
Copyright notice © 2018 Author(s). All article content, except where otherwise noted, is licensed under a Creative Commons Attribution (CC BY) License
ISSN 2378-0967
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