"Do-it-in-classroom" fabrication of microfluidic systems by replica moulding of pasta structures

Nguyen, T, Thurgood, P, Zhu, J, Pirogova, E, Baratchi, S and Khoshmanesh, K 2018, '"Do-it-in-classroom" fabrication of microfluidic systems by replica moulding of pasta structures', Biomicrofluidics, vol. 12, no. 4, pp. 1-14.


Document type: Journal Article
Collection: Journal Articles

Title "Do-it-in-classroom" fabrication of microfluidic systems by replica moulding of pasta structures
Author(s) Nguyen, T
Thurgood, P
Zhu, J
Pirogova, E
Baratchi, S
Khoshmanesh, K
Year 2018
Journal name Biomicrofluidics
Volume number 12
Issue number 4
Start page 1
End page 14
Total pages 14
Publisher American Institute of Physics
Abstract Here, we describe a novel method for fabrication of microfluidic structures in classroom environments. This method is based on replica moulding of pasta structures in polydimethylsiloxane. Placing pasta structures on a petroleum jelly base layer enables templating round-shaped structures with controllable cross-sectional profiles. The pasta structures can be easily deformed and combined to create more complex 3D microfluidic structures. Proof-of-concept experiments indicate the capability of this method for studying the mixing of neighbouring flows, generation of droplets, lateral migration of particles, as well as culturing, shear stress stimulation, and imaging of cells. Our "do-it-in-classroom" method bridges the gap between the classroom and the laboratory.
Subject Microtechnology
Nanobiotechnology
Keyword(s) Microfluidics
Fabrication
DOI - identifier 10.1063/1.5042684
ISSN 1932-1058
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