Synthesis and characterization of wool keratin/hydroxyapatite nanocomposite

Li, J, Liu, X, Zhang, J, Zhang, Y, Han, Y, Hu, J and Li, Y 2012, 'Synthesis and characterization of wool keratin/hydroxyapatite nanocomposite', Journal of Biomedical Materials Research - Part B Applied Biomaterials, vol. 100B, no. 4, pp. 896-902.


Document type: Journal Article
Collection: Journal Articles

Title Synthesis and characterization of wool keratin/hydroxyapatite nanocomposite
Author(s) Li, J
Liu, X
Zhang, J
Zhang, Y
Han, Y
Hu, J
Li, Y
Year 2012
Journal name Journal of Biomedical Materials Research - Part B Applied Biomaterials
Volume number 100B
Issue number 4
Start page 896
End page 902
Total pages 7
Publisher John Wiley & Sons
Abstract Taking the inspiration from the biomineral, the wool keratin was selected to modulate the assembly of nanosized hydroxyapatite (HA) crystals via a coprecipitation method. A series of keratin/HA nanocomposite with different ratios were synthesized by adjusting the concentrations of keratin solutions and calcium phosphate and their final components were detected by thermogravimetric analysis (TGA). The transmission electron microscopy (TEM) and X‐ray diffraction (XRD) confirmed that keratin in the composite decreased the crystallinity of HA. Fourier transform infrared (FTIR) and X‐ray photoelectron spectroscopy (XPS) were used to examine the chemical and surface structure of the composites. In vitro biocompatibility results revealed that cells showed better viability on keratin/HA composites which have a ratio of organics and inorganics similar to that of natural bones.
Subject Biomaterials
Keyword(s) biomimetic
composite
hydroxyapatite
keratin
nanomaterials
DOI - identifier 10.1002/jbm.b.32645
Copyright notice © 2012 Wiley Periodicals, Inc. J Biomed Mater Res Part B: Appl Biomater, 2012.
ISSN 1552-4973
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