Three-dimensional reconstruction of the giant mimivirus particle with an X-ray free-electron laser

Ekeberg, T, Svenda, M, Abergel, C and Martin, A 2015, 'Three-dimensional reconstruction of the giant mimivirus particle with an X-ray free-electron laser', Physical Review Letters, vol. 114, no. 9, 098102, pp. 1-6.


Document type: Journal Article
Collection: Journal Articles

Title Three-dimensional reconstruction of the giant mimivirus particle with an X-ray free-electron laser
Author(s) Ekeberg, T
Svenda, M
Abergel, C
Martin, A
Year 2015
Journal name Physical Review Letters
Volume number 114
Issue number 9
Article Number 098102
Start page 1
End page 6
Total pages 6
Publisher American Physical Society
Abstract We present a proof-of-concept three-dimensional reconstruction of the giant mimivirus particle from experimentally measured diffraction patterns from an x-ray free-electron laser. Three-dimensional imaging requires the assembly of many two-dimensional patterns into an internally consistent Fourier volume. Since each particle is randomly oriented when exposed to the x-ray pulse, relative orientations have to be retrieved from the diffraction data alone. We achieve this with a modified version of the expand, maximize and compress algorithm and validate our result using new methods.
Subject Condensed Matter Imaging
DOI - identifier 10.1103/PhysRevLett.114.098102
Copyright notice © 2015 American Physical Society.
ISSN 0031-9007
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