• RMIT Australia
  • RMIT Global
  • RMIT Australia
  • RMIT Europe
  • RMIT Vietnam

• Students
• Alumni
• Staff

Research Repository

Back to Library

• Home
• Browse
• Search
• FAQs
• About
• Contact Us

Near superhydrophobic fibrous scaffold for endothelialization: Fabrication, characterization and cellular activities Ahmed, F, Choudhury, N, Dutta, N, Zannettino, A and Knott, R 2013, 'Near superhydrophobic fibrous scaffold for endothelialization: Fabrication, characterization and cellular activities', Biomacromolecules, vol. 14, no. 11, pp. 3850-3860. Document type: Journal Article Collection: Journal Articles Title Near superhydrophobic fibrous scaffold for endothelialization: Fabrication, characterization and cellular activities Author(s) Ahmed, F Choudhury, N Dutta, N Zannettino, A Knott, R Year 2013 Journal name Biomacromolecules Volume number 14 Issue number 11 Start page 3850 End page 3860 Total pages 11 Publisher American Chemical Society Abstract In this work, we have applied an electrospinning method to control wettability and further hydrophobic modification of a hydrophobic polymer mat of poly(vinylidene fluoride-co-hexafluoropropylene). A correlation between the processing parameters, rheological properties of polymer solutions, and electrospinning ability was made using the polymer's critical entanglement concentration, the boundary between the semidilute unentangled regime and the semidilute entangled regime. The wetting behavior, structural and thermal characteristics of electrospun (ES) mats were evaluated and compared with solvent cast sample using advancing and receding contact angle analyses, differential scanning calorimetry, and small-angle X-ray scattering. To demonstrate the feasibility, the best optimized ES samples were examined for their potential and ability to support bone marrow derived endothelial cell seeding efficiency, adhesion and proliferation. Our studies show that, while different processing techniques can effectively modulate physical and morphological changes such as porosity and hydrophobicity, the cellular adhesion and proliferation are highly time-dependent and controlled by chemical factors. As such, these results suggest that it is the interplay of both physical and chemical factors that determine the endothelialization of porous near superhydrophobic scaffolds. The developed electrospun samples demonstrate their feasibility for endothelialization. Subject Biomaterials Chemical Engineering not elsewhere classified DOI - identifier 10.1021/bm400938n Copyright notice © 2013 American Chemical Society. ISSN 1525-7797 Related Links Link Description https://dx.doi.org/10.1021/bm400938n Link to Published Version   Versions Version Filter Type Thu, 31 Jan 2019, 14:10:19 EST Filtered Full Citation counts:   Cited 16 times in Thomson Reuters Web of Science Article | Citations Cited 0 times in Scopus Article Altmetric details: Access Statistics: 3 Abstract Views  -  Detailed Statistics Created: Thu, 31 Jan 2019, 11:26:00 EST by Catalyst Administrator