Biomimetic protein-based elastomeric hydrogels for biomedical applications

Whittaker, J, Balu, R, Choudhury, N and Dutta, N 2014, 'Biomimetic protein-based elastomeric hydrogels for biomedical applications', Polymer International, vol. 63, no. 9, pp. 1545-1557.


Document type: Journal Article
Collection: Journal Articles

Title Biomimetic protein-based elastomeric hydrogels for biomedical applications
Author(s) Whittaker, J
Balu, R
Choudhury, N
Dutta, N
Year 2014
Journal name Polymer International
Volume number 63
Issue number 9
Start page 1545
End page 1557
Total pages 13
Publisher John Wiley & Sons Ltd.
Abstract In recent years, protein-based elastomeric hydrogels have gained increased research interest in biomedical applications for their remarkable self-assembly behaviour, tunable 3D porous structure, high resilience (elasticity), fatigue lifetime (durability), water uptake, excellent biocompatibility and biological activity. The proteins and polypeptides can be derived naturally (animal or insect sources) or by recombinant (bacterial expression) routes and can be crosslinked via physical or chemical approaches to obtain elastomeric hydrogels. Here we review and present the recent accomplishments in the synthesis, fabrication and biomedical applications of protein-based elastomeric hydrogels such as elastin, resilin, flagelliform spider silk and their derivatives.
Subject Biomaterials
Chemical Engineering not elsewhere classified
Keyword(s) Biomimetic proteins
Elastomers
Hydrogels
Regenerative medicine
Tissue engineering
DOI - identifier 10.1002/pi.4670
Copyright notice © 2013 Society of Chemical Industry.
ISSN 0959-8103
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