A meta-analysis evaluating the relationship between aquatic contaminants and chironomid larval deformities in laboratory studies

Gagliardi, B, Pettigrove, V, Long, S and Hoffmann, A 2016, 'A meta-analysis evaluating the relationship between aquatic contaminants and chironomid larval deformities in laboratory studies', Environmental Science and Technology, vol. 50, no. 23, pp. 12903-12911.


Document type: Journal Article
Collection: Journal Articles

Title A meta-analysis evaluating the relationship between aquatic contaminants and chironomid larval deformities in laboratory studies
Author(s) Gagliardi, B
Pettigrove, V
Long, S
Hoffmann, A
Year 2016
Journal name Environmental Science and Technology
Volume number 50
Issue number 23
Start page 12903
End page 12911
Total pages 9
Publisher American Chemical
Abstract Chironomid larval deformities have been widely investigated as an aquatic pollution toxicity end point. Field chironomid surveys often show a spatial association between contaminants and deformities, suggesting contaminants cause deformities. However, over 40 years of laboratory assays have not been able to confirm this causality. We therefore conducted a review of the literature and meta-analysis, in order to (A) assess whether trends across assays indicated dose-response effects, (B) characterize the consistency of results, and (C) investigate whether experimental issues and publication bias were contributing to inconsistency and/or reducing confidence in results. The experimental issues we investigated were extraneous nonchemical laboratory stressors (which may mask or interact with chemical effects), and mortality (which can confound deformity results). Our meta-analysis of the most commonly tested chemicals suggested dose-response effects for copper, but not lead or zinc. However, we also found substantial inconsistency across studies. Both mortality and extraneous stressors were potentially contributing to this inconsistency, reducing confidence in most published data. We observed no evidence of publication bias. We conclude that any causal link between contaminants and deformities remains uncertain, and suggest improved experimental and data reporting procedures to better assess this relationship.
Subject Freshwater Ecology
DOI - identifier 10.1021/acs.est.6b04020
Copyright notice © 2016 American Chemical Society
ISSN 0013-936X
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 4 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 0 times in Scopus Article
Altmetric details:
Access Statistics: 3 Abstract Views  -  Detailed Statistics
Created: Thu, 31 Jan 2019, 11:26:00 EST by Catalyst Administrator
© 2014 RMIT Research Repository • Powered by Fez SoftwareContact us