Recent advances in biodegradation controls over Mg alloys for bone fracture management: A review

Song, M, Zeng, R, Ding, Y, Li, R, Easton, M, Cole, I, Birbilis, N and Chen, X 2019, 'Recent advances in biodegradation controls over Mg alloys for bone fracture management: A review', Journal of Materials Science and Technology, vol. 35, no. 4, pp. 535-544.


Document type: Journal Article
Collection: Journal Articles

Title Recent advances in biodegradation controls over Mg alloys for bone fracture management: A review
Author(s) Song, M
Zeng, R
Ding, Y
Li, R
Easton, M
Cole, I
Birbilis, N
Chen, X
Year 2019
Journal name Journal of Materials Science and Technology
Volume number 35
Issue number 4
Start page 535
End page 544
Total pages 10
Publisher Zhongguo Kexueyuan Jinshu Yanjiusuo
Abstract Magnesium (Mg) alloys possess comparable physical and mechanical properties to bone, making them an outstanding candidate of implant materials for bone fracture treatment. In addition to the excellent biocompatibility, and bioactivity, the engagement of Mg alloys is key for a number of biological functionalities in the human body. The unique biodegradation nature of Mg alloy implants implies that it may not require a secondary removal procedure when the expected supporting tasks accomplish, as they may simply and safely "disappear" over time. Nonetheless, the demonstrated drawback of potentially rapid degradation, is an issue that must be addressed appropriately for Mg implants and is consequently given unique attention in this review article. Herein, the critical criteria and the state-of-the-art strategies for controlling the degradation process of Mg alloys are reported. Furthermore, future developments of biodegradable Mg and its alloys systems with satisfactory specifications for clinical trials and deployment, are discussed. This review aims to provide information to materials scientists and clinical practitioners in the context of developing practical biodegradable Mg alloys.
Subject Metals and Alloy Materials
Functional Materials
Keyword(s) Biodegradation
Corrosion mechanisms
Cytocompatibility
Magnesium alloys
DOI - identifier 10.1016/j.jmst.2018.10.008
Copyright notice © 2019 Published by Elsevier Ltd on behalf of The editorial office of Journal of Materials Science & Technology
ISSN 1005-0302
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 11 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 0 times in Scopus Article
Altmetric details:
Access Statistics: 45 Abstract Views  -  Detailed Statistics
Created: Thu, 31 Jan 2019, 11:26:00 EST by Catalyst Administrator
© 2014 RMIT Research Repository • Powered by Fez SoftwareContact us