Breathomics and Its Application for Disease Diagnosis: A Review of Analytical Techniques and Approaches

Beale, D, Jones, O, Karpe, A, Oh, D, White, I, Kouremenos, K and Palombo, E 2018, 'Breathomics and Its Application for Disease Diagnosis: A Review of Analytical Techniques and Approaches' in Raquel Cumeras and Xavier Correig (ed.) Volatile Organic Compounds Analysis in Biomedical Diagnosis Applications, Apple Academic Press, New York, USA, pp. 159-194.


Document type: Book Chapter
Collection: Book Chapters

Title Breathomics and Its Application for Disease Diagnosis: A Review of Analytical Techniques and Approaches
Author(s) Beale, D
Jones, O
Karpe, A
Oh, D
White, I
Kouremenos, K
Palombo, E
Year 2018
Title of book Volatile Organic Compounds Analysis in Biomedical Diagnosis Applications
Publisher Apple Academic Press
Place of publication New York, USA
Editor(s) Raquel Cumeras and Xavier Correig
Start page 159
End page 194
Subjects Analytical Biochemistry
Separation Science
Cell Metabolism
Summary The application of metabolomics to an ever-greater variety of sample types is a key focus of systems biology research. Recently, there has been a strong focus on applying these approaches toward the rapid analysis of metabolites found in non-invasively acquired samples, such as exhaled breath (also known as 'breathomics'). The sampling process involved in collecting exhaled breath is non-intrusive and comparatively low-cost. It uses a series of globally approved methods and provides researchers with easy access to the metabolites secreted by the human body. Owing to its accuracy and rapid nature, metabolomic analysis of breath is a rapidly growing field that has proven effective in detecting and diagnosing the early stages of numerous diseases and infections. This review discusses the various collection and analysis methods currently applied in breathomics research. Some of the salient research completed in this field to date is also assessed and discussed in order to provide a basis for possible future scientific directions.
Copyright notice © Apple Academic Press 2019
ISBN 9781771887441
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