Holybasil (tulsi) lowers fasting glucose and improved lipid profile in adults with metabolic disease: A meta-analysis of randomized clinical trials

Jamshidi, N, Da Costa, C and Cohen, M 2018, 'Holybasil (tulsi) lowers fasting glucose and improved lipid profile in adults with metabolic disease: A meta-analysis of randomized clinical trials', Journal of Functional Foods, vol. 45, pp. 47-57.


Document type: Journal Article
Collection: Journal Articles

Title Holybasil (tulsi) lowers fasting glucose and improved lipid profile in adults with metabolic disease: A meta-analysis of randomized clinical trials
Author(s) Jamshidi, N
Da Costa, C
Cohen, M
Year 2018
Journal name Journal of Functional Foods
Volume number 45
Start page 47
End page 57
Total pages 11
Publisher Elsevier BV
Abstract Objective: To examine the effect of holy basil (tulsi) on metabolic syndrome parameters. Methods: Electronic database searches using relevant MeSH, free text terms and manual searches of the key references was performed up to August 2017. Study quality was evaluated using the Jadad scale. Effect size estimates were calculated as Mean Differences with 95% confidence interval(CI) using the random-effects model. Results: Consumption of tulsi significantly lowered mean fasting blood glucose [pooled MD: ?15.69, 95% CI: ?28.67 to ?2.70; p = 0.02, I2 = 91.22%] compared to control interventions. Subgroup analysis further revealed total, LDL and VLDL cholesterol levels were significantly reduced in older participants with metabolic disease. Conclusions: Short-term effects of tulsi as a single herb was effective at reducing fasting blood glucose. In older (?40 years) patients with metabolic disease tulsi supplementation at higher doses (?1 g/day) is associated with a reduction in total, LDL and VLDL cholesterol without changing overall lipid profiles.
Subject Applied Statistics
Complementary and Alternative Medicine not elsewhere classified
Keyword(s) Ayurveda
Cholesterol
Diabetes
Glucose
Metabolic disorders
Ocimum sanctum
DOI - identifier 10.1016/j.jff.2018.03.030
Copyright notice © 2018 Published by Elsevier Ltd.
ISSN 1756-4646
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