Saccharomyces-derived carbon dots for biosensing pH and vitamin B 12

Yu, Y, Li, C, Chen, C, Huang, H, Liang, C, Lou, Y, Chen, X, Shi, Z and Feng, S 2019, 'Saccharomyces-derived carbon dots for biosensing pH and vitamin B 12', Talanta, vol. 195, pp. 117-126.


Document type: Journal Article
Collection: Journal Articles

Title Saccharomyces-derived carbon dots for biosensing pH and vitamin B 12
Author(s) Yu, Y
Li, C
Chen, C
Huang, H
Liang, C
Lou, Y
Chen, X
Shi, Z
Feng, S
Year 2019
Journal name Talanta
Volume number 195
Start page 117
End page 126
Total pages 10
Publisher Elsevier
Abstract Photoluminescence(PL) nano-biosensors that can be used for accurately and reliably monitoring pH and vitamin hold a great promise in biology and medicine. Herein, a high quantum yield of 16% saccharomyces-derived N-doped carbon dots (s-N-CDs) was synthesized through a simple and one-pot microwave-assisted hydrothermal approach. The produced s-N-CDs are an excellent multi-functional biosensor for the applications of pH sensing and vitamin probing. Fluorescence intensity and fluorescence lifetime dramatically increases with pH decreasing from 14 to 2. Moreover, the fluorescence intensity presents highly reversible abilty from 13 to 2 without any profound attenuation after ten consecutive circles. More importantly, the CDs prepared herein are sound option for assaying cobalamin (VB 12) based fluorescence resonance energy transfer (FRET) with a superior low detection limit of 2.19 mu M.
Subject Composite and Hybrid Materials
Functional Materials
Keyword(s) Biosensor
Carbon dots
pH
Saccharomyces
Vitamin B 12
DOI - identifier 10.1016/j.talanta.2018.11.010
Copyright notice © 2018 Elsevier
ISSN 0039-9140
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