Nanocellulose reinforced P(AAm-co-AAc) hydrogels with improved mechanical properties and biocompatibility

Huang, S, Zhao, Z, Feng, C, Mayes, E and Yang, J 2018, 'Nanocellulose reinforced P(AAm-co-AAc) hydrogels with improved mechanical properties and biocompatibility', Composites Part A: Applied Science and Manufacturing, vol. 112, pp. 395-404.


Document type: Journal Article
Collection: Journal Articles

Title Nanocellulose reinforced P(AAm-co-AAc) hydrogels with improved mechanical properties and biocompatibility
Author(s) Huang, S
Zhao, Z
Feng, C
Mayes, E
Yang, J
Year 2018
Journal name Composites Part A: Applied Science and Manufacturing
Volume number 112
Start page 395
End page 404
Total pages 10
Publisher Pergamon Press
Abstract Carboxylate modified cellulose nanofibril (CNF) was used to reinforce poly(acrylamide-co-acrylic acid) (P(AAm-co-AAc)) hydrogel via in-situ polymerization. With introduction of Fe3+-carboxylate complexation, a dual cross-linking network structure in the P(AAm-co-AAc)/CNF hydrogels was constructed, i.e. the covalently cross-linked acrylic components forming a macromolecular network, and the noncovalently COO--Fe3+ionic coordination bonds acting as secondary cross-linking points. The microstructure of the hydrogels was characterized by scanning electron microscopy (SEM). By incorporating 0.6 wt% CNF, the elastic modulus, tensile strength and toughness of P(AAm-co-AAc) hydrogel were improved by 240%, 104% and 51%, respectively. The addition of CNF also enhanced the energy dissipation in loading and unloading tests. P(AAm-co-AAc)/CNF nanocomposite hydrogels showed water content (70-80%) comparable with that in human cartilage (75%). The biocompatibility tests suggested that P(AAm-co-AAc)/CNF had no toxicity to cells and cells can adhere and proliferate well on the surface, making it suitable for biomedical and tissue engineering applications.
Subject Solid Mechanics
Nanomaterials
Keyword(s) Biocompatibility
Cellulose nanofibril
Hydrogel
Mechanical properties
DOI - identifier 10.1016/j.compositesa.2018.06.028
Copyright notice © 2018 Elsevier Ltd. All rights reserved.
ISSN 1359-835X
Versions
Version Filter Type
Citation counts: TR Web of Science Citation Count  Cited 3 times in Thomson Reuters Web of Science Article | Citations
Scopus Citation Count Cited 0 times in Scopus Article
Altmetric details:
Access Statistics: 9 Abstract Views  -  Detailed Statistics
Created: Tue, 26 Mar 2019, 09:36:00 EST by Catalyst Administrator
© 2014 RMIT Research Repository • Powered by Fez SoftwareContact us