Theoretical estimation for correlations of diffraction patterns from objects differently oriented in space

Ziaja, B, Martin, A, Wang, F, Chapman, H and Weckert, E 2011, 'Theoretical estimation for correlations of diffraction patterns from objects differently oriented in space', Ultramicroscopy, vol. 111, no. 7, pp. 793-797.


Document type: Journal Article
Collection: Journal Articles

Title Theoretical estimation for correlations of diffraction patterns from objects differently oriented in space
Author(s) Ziaja, B
Martin, A
Wang, F
Chapman, H
Weckert, E
Year 2011
Journal name Ultramicroscopy
Volume number 111
Issue number 7
Start page 793
End page 797
Total pages 5
Publisher Elsevier BV
Abstract Coherent diffraction imaging of single biomolecules is expected to open unique opportunities for studies of non-crystalline samples. There are, however, still many technical and physical issues that need to be resolved in a more quantitative manner, especially if one aims for structural information at high resolution. Signal recorded from an object after a single shot is low. As primarily proposed in Spence and Doak (2004) and Huldt et al. (2003) [1,2], averaging over the diffraction patterns from many different shots is necessary, in order to achieve a signal-to-noise ratio sufficient for image reconstruction. The images of the randomly oriented molecules have to be sorted out in order to identify those corresponding to the similar spatial orientations of the objects. This procedure is called the classification of diffraction images. Here we approach the classification in the framework of pattern-to-pattern correlations, and analyse theoretically the correlations between diffraction images of differently oriented objects.
Subject Condensed Matter Imaging
Keyword(s) Classification
Coherent diffraction imaging
Free-electron laser
DOI - identifier 10.1016/j.ultramic.2010.12.021
Copyright notice © 2011 Elsevier BV
ISSN 0304-3991
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