The Evolving Facets of Bacterial Vaginosis: Implications for HIV Transmission

McKinnon, L, Achilles, S, Bradshaw, C and Tachedjian, G., et al, 2019, 'The Evolving Facets of Bacterial Vaginosis: Implications for HIV Transmission', AIDS Research and Human Retroviruses, vol. 35, no. 3, pp. 219-228.


Document type: Journal Article
Collection: Journal Articles

Title The Evolving Facets of Bacterial Vaginosis: Implications for HIV Transmission
Author(s) McKinnon, L
Achilles, S
Bradshaw, C
Tachedjian, G., et al,
Year 2019
Journal name AIDS Research and Human Retroviruses
Volume number 35
Issue number 3
Start page 219
End page 228
Total pages 10
Publisher Mary Ann Liebert, Inc. Publishers
Abstract Bacterial vaginosis (BV) is a common yet poorly understood vaginal condition that has become a major focus of HIV transmission and immunology research. Varied terminologies are used by clinicians and researchers to describe microbial communities that reside in the female reproductive tract (FRT), which is driven, in part, by microbial genetic and metabolic complexity, evolving diagnostic and molecular techniques, and multidisciplinary perspectives of clinicians, epidemiologists, microbiologists, and immunologists who all appreciate the scientific importance of understanding mechanisms that underlie BV. This Perspectives article aims to clarify the varied terms used to describe the cervicovaginal microbiota and its "nonoptimal" state, under the overarching term of BV. The ultimate goal is to move toward language standardization in future literature that facilitates a better understanding of the impact of BV on FRT immunology and risk of sexually transmitted infections, including HIV.
Subject Clinical Sciences not elsewhere classified
Keyword(s) bacterial vaginosis
female reproductive tract
genital inflammation
HIV
HIV transmission
vaginal microbiota
DOI - identifier 10.1089/aid.2018.0304
Copyright notice © Lyle R. McKinnon et al. 2019; Published by Mary Ann Liebert, Inc. This Open Access article is distributed under the terms of the Creative Commons License (http://creativecommons.org/licenses/by/4.0)
ISSN 0889-2229
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