Proteomic analysis of hypertrophied myocardial protein patterns in renovascularly hypertensive and spontaneously hypertensive rats

Zhou, S, Zhou, S, Huang, H, Chen, J and Liu, P 2006, 'Proteomic analysis of hypertrophied myocardial protein patterns in renovascularly hypertensive and spontaneously hypertensive rats', Journal of Proteome Research, vol. 5, no. 11, pp. 2901-2908.


Document type: Journal Article
Collection: Journal Articles

Title Proteomic analysis of hypertrophied myocardial protein patterns in renovascularly hypertensive and spontaneously hypertensive rats
Author(s) Zhou, S
Zhou, S
Huang, H
Chen, J
Liu, P
Year 2006
Journal name Journal of Proteome Research
Volume number 5
Issue number 11
Start page 2901
End page 2908
Total pages 8
Publisher American Chemical Society
Abstract The cardiac protein profiles of spontaneously hypertensive and renovascularly hypertensive hypertrophy showed a significant alteration compared with normal hearts. Most proteins with significant modulations in their expressions belong to the category of metabolic and stress-related proteins. Among these proteins, glutathione-S-transferase mu2 and short-chain acyl-CoA dehydrogenase may be two candidate proteins associated with left ventricular hypertrophy in spontaneously hypertensive rats.
Subject Basic Pharmacology
DOI - identifier 10.1021/pr050456l
ISSN 1535-3893
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