Acupuncture for persistent allergic rhinitis: a randomised, sham-controlled trial

Xue, C, An, X, Cheung, T, Da Costa, C, Lenon, G, Thien, F and Story, D 2007, 'Acupuncture for persistent allergic rhinitis: a randomised, sham-controlled trial', Medical Journal of Australia, vol. 187, pp. 337-341.

Document type: Journal Article
Collection: Journal Articles

Title Acupuncture for persistent allergic rhinitis: a randomised, sham-controlled trial
Author(s) Xue, C
An, X
Cheung, T
Da Costa, C
Lenon, G
Thien, F
Story, D
Year 2007
Journal name Medical Journal of Australia
Volume number 187
Start page 337
End page 341
Total pages 5
Publisher Australasian Medical Publishing Company
Abstract OBJECTIVE - To investigate the effectiveness and safety of acupuncture in persistent allergic rhinitis (PAR). DESIGN - Randomised, single-blind, sham-controlled trial conducted from May 2004 to February 2005. PARTICIPANTS & INTERVENTION - 80 patients with PAR (age, 16-70 years) were randomly assigned to receive real or sham acupuncture. After a 1-week baseline period, participants were treated twice weekly for 8 weeks and followed up for another 12 weeks. MAIN OUTCOME MEASURES - Nasal obstruction, sneezing, rhinorrhoea and nasal itch were each self-assessed daily on a 5-point scale, and scores were aggregated weekly. The sum of the symptom scores (total nasal symptom score, TNSS) was also determined. A secondary outcome was use of PAR relief medication. RESULTS - After 8 weeks' treatment, the weekly mean difference in TNSS from baseline was greater with real (-17.2; 95% CI, -24.6 to -9.8) than with sham acupuncture (-4.2; 95% CI, -11.0 to 2.7) (P = 0.01). The decrease in individual symptom score was also greater with real acupuncture for rhinorrhoea (P < 0.01) but not the other symptoms. At the end of follow-up, the greater difference in TNSS from baseline in the real acupuncture group was still apparent: real, -21.0 (95% CI, -29.1 to -12.9) versus sham, -2.3 (95% CI, -10.2 to 5.6) (P = 0.001). Moreover, the differences from baseline in all four individual symptom scores were greater for the real than for the sham group (P < 0.05). Real and sham acupuncture were both well tolerated. CONCLUSION - Our findings suggest that acupuncture is effective in the symptomatic treatment of PAR.
Subject Traditional Chinese Medicine and Treatments
Keyword(s) Controlled Clinical-Trial
Placebo-Controlled Trial
Chinese Herbal Medicine
Copyright notice © The Medical Journal of Australia 2007
ISSN 0025-729X
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Citation counts: TR Web of Science Citation Count  Cited 52 times in Thomson Reuters Web of Science Article | Citations
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