Simulation of arterial stenosis incorporating fluid-structural interaction and non-Newtonian blood flow

Chan, W 2006, Simulation of arterial stenosis incorporating fluid-structural interaction and non-Newtonian blood flow, Masters by Research, Aerospace, Mechanical and Manufacturing Engineering, RMIT University.


Document type: Thesis
Collection: Theses

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Title Simulation of arterial stenosis incorporating fluid-structural interaction and non-Newtonian blood flow
Author(s) Chan, W
Year 2006
Abstract The aim of this study is to investigate the fluid-structural response to pulsatile Newtonian and non-Newtonian blood flow through an axisymmetric stenosed vessel using FLOTRAN and ANSYS. This is to provide a basic understanding of atherosclerosis. The flow was set to be laminar and follows a sinusoidal waveform. The solid model was set to have isotropic elastic properties. The Fluid-Structural Interaction (FSI) coupling was two-way and iterative. Rigid and Newtonian cases were investigated to provide an understanding on the effects of incorporating FSI into the model. The wall expansion was found to decrease the axial velocity and increase the recirculation effects of the flow. To validate the models and methods used, the results were compared with the study by Lee and Xu [2002] and Ohja et al [1989]. Close comparisons were achieved, suggesting the models used were valid. Two non-Newtonian models were investigated with FSI: Carreau and Power Law models. The Carreau model fluid behaviour was very close to the Newtonian model. The Power Law model produced significant difference in viscosity, velocity and wall shear stress distributions. Pressure distribution for all models was similar. In order to quantify the changes, Importance Factor (IG) was introduced to determine the overall non-Newtonian effects at two regions: the entire flow model and about the vessel wall. The Carreau model showed reasonable values of IG whereas the Power Law model showed excessive values. Transient and geometrical effects were found to affect the Importance Factor. The stress distributions for all models were found to be similar. Highest stress occurred at the shoulders of the stenosis where a stress concentration occurred due to sharp corners of the geometry and large bending moments. The highest stresses were in the axial direction. Notable circumferential stress was found at the ends of the vessel. Carreau model produced slightly higher stresses than the other models. Wall stresses were found to be primarily influenced by internal pressure, rather than wall shear stresses.
Degree Masters by Research
Institution RMIT University
School, Department or Centre Aerospace, Mechanical and Manufacturing Engineering
Keyword(s) fluid-structural
interaction
FSI
fluid-solid
non-Newtonian
blood
stenosis
FLOTRAN
ANSYS
power law
Carreau
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Created: Tue, 22 Feb 2011, 15:41:35 EST by Guy Aron
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