Assessment of out-of-field doses in radiotherapy of brain lesions in children

Taylor, M, Kron, T and Franich, R 2011, 'Assessment of out-of-field doses in radiotherapy of brain lesions in children', International Journal of Radiation Oncology Biology Physics, vol. 79, no. 3, pp. 927-933.

Document type: Journal Article
Collection: Journal Articles

Title Assessment of out-of-field doses in radiotherapy of brain lesions in children
Author(s) Taylor, M
Kron, T
Franich, R
Year 2011
Journal name International Journal of Radiation Oncology Biology Physics
Volume number 79
Issue number 3
Start page 927
End page 933
Total pages 7
Publisher Elsevier Inc.
Abstract Purpose: To characterize the out-of-field doses in pediatric radiotherapy and to identify simple methods by which out-of-field dose might be minimized, with a view to reducing the risk of secondary cancers. Methods and Materials: With the aim of characterizing the peripheral doses under different treatment conditions, the dose measurements in an anthropomorphic child phantom were taken in various organs and critical structures outside the primary field using thermoluminescent dosimetry. The doses from a Varian 600C and Varian Trilogy linear accelerator, both at 6 MV, were investigated. Results: Larger field sizes have been shown to result in greater peripheral doses close to the primary beam, with the difference becoming less significant at large distances, indicating that most of out-of-field doses result from head leakage and collimator scatter >40 cm from the primary field. The use of lead shields has been shown to reduce the absorbed dose resulting from leakage. Aligning the craniocaudal axis of the patient with the x-plane of the collimator resulted in a dose reduction of 40%, for both machines. Out-of-field doses from the Varian Trilogy were shown to be approximately 40% greater than those from the 600C linear accelerator, despite being operated at the same energy. Conclusion: Out-of-field doses to pediatric patients can be minimized by using simple treatment options, such as using the single-energy mode linear accelerator rather than the multimode, orienting the couch and collimator such that the patient lies along the x-plane and avoiding fields directed along the trunk of the body.
Subject Medical Physics
Physical Sciences not elsewhere classified
Keyword(s) Pediatric
Peripheral dose
DOI - identifier 10.1016/j.ijrobp.2010.04.064
Copyright notice © 2011 Elsevier Inc.
ISSN 0360-3016
NHMRC Grant ID 555420
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Citation counts: TR Web of Science Citation Count  Cited 20 times in Thomson Reuters Web of Science Article | Citations
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