A bioactive peptide analogue for myxoma virus protein with a targeted cytotoxicity for human skin cancer in vitro

ALMANSOUR, N, Pirogova, E, Coloe, P, Cosic, I and Istivan, T 2012, 'A bioactive peptide analogue for myxoma virus protein with a targeted cytotoxicity for human skin cancer in vitro', Journal of Biomedical Science, vol. 19, no. 65, pp. 1-13.


Document type: Journal Article
Collection: Journal Articles

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Title A bioactive peptide analogue for myxoma virus protein with a targeted cytotoxicity for human skin cancer in vitro
Author(s) ALMANSOUR, N
Pirogova, E
Coloe, P
Cosic, I
Istivan, T
Year 2012
Journal name Journal of Biomedical Science
Volume number 19
Issue number 65
Start page 1
End page 13
Total pages 13
Publisher BioMed Central Ltd.
Abstract Background - Cancer is an international health problem, and the search for effective treatments is still in progress. Peptide therapy is focused on the development of short peptides with strong tumoricidal activity and low toxicity. In this study, we investigated the efficacy of a myxoma virus peptide analogue (RRM-MV) as a candidate for skin cancer therapy. RRM-MV was designed using the Resonant Recognition Model (RRM) and its effect was examined on human skin cancer and normal human skin cells in vitro.
Subject Cell Development, Proliferation and Death
Virology
Biomedical Engineering not elsewhere classified
Keyword(s) RRM-MV
Myxoma virus
Bioactive peptide
Melanoma
Carcinoma
DOI - identifier 10.1186/1423-0127-19-65
Copyright notice © 2012 Almansour et al
ISSN 1021-7770
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