Antiviral activity of arbidol, a broad-spectrum drug for used against respiratory viruses, varies according to test conditions

Brooks, M, Burtseva, E, Ellery, P, Marsh, G, Lew, A, Slepushhkin, A, Crowe, S and Tannock, G 2012, 'Antiviral activity of arbidol, a broad-spectrum drug for used against respiratory viruses, varies according to test conditions', Journal of Medical Virology, vol. 84, no. 1, pp. 170-181.


Document type: Journal Article
Collection: Journal Articles

Title Antiviral activity of arbidol, a broad-spectrum drug for used against respiratory viruses, varies according to test conditions
Author(s) Brooks, M
Burtseva, E
Ellery, P
Marsh, G
Lew, A
Slepushhkin, A
Crowe, S
Tannock, G
Year 2012
Journal name Journal of Medical Virology
Volume number 84
Issue number 1
Start page 170
End page 181
Total pages 12
Publisher John Wiley & Sons
Abstract The therapeutic activity of arbidol was investigated against representatives of seven different virus families. Its 50% median effective concentration (EC 50) was 0.22-11.8µg/ml (0.41-22nM). Therapeutic indices of 91 were obtained for type 1 poliovirus and 1.9-8.5 for influenza A and B, human paramyxo-3, avian infectious bronchitis-, and Marek's disease viruses.
Subject Microbiology not elsewhere classified
Biological Sciences not elsewhere classified
Keyword(s) Antiviral
broad-spectrum
conditions
respiratory
DOI - identifier 10.1002/jmv.22234
Copyright notice © 2011 Wiley Periodicals
ISSN 0146-6615
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