An in vivo investigative protocol for HDR prostate brachytherapy using urethral and rectal thermoluminescence dosimetry

Toye, W, Das, R, Kron, T, Franich, R, Johnston, P and Duchesne, G 2009, 'An in vivo investigative protocol for HDR prostate brachytherapy using urethral and rectal thermoluminescence dosimetry', Radiotherapy and Oncology, vol. 91, no. 2, pp. 243-248.


Document type: Journal Article
Collection: Journal Articles

Title An in vivo investigative protocol for HDR prostate brachytherapy using urethral and rectal thermoluminescence dosimetry
Author(s) Toye, W
Das, R
Kron, T
Franich, R
Johnston, P
Duchesne, G
Year 2009
Journal name Radiotherapy and Oncology
Volume number 91
Issue number 2
Start page 243
End page 248
Total pages 5
Publisher Elsevier Ireland Ltd
Abstract Purpose: To develop an in vivo dosimetry based investigative action level relevant for a corrective protocol for HDR brachytherapy boost treatment. Methods and materials The dose delivered to points within the urethra and rectum was measured using TLD in vivo dosimetry in 56 patients. Comparisons between the urethral and rectal measurements and TPS calculations showed differences, which are related to the relative position of the implant and TLD trains, and allowed shifts of implant position relative to the prostate to be estimated. Results and conclusions Analysis of rectal dose measurements is consistent with implant movement, which was previously only identified with the urethral data. Shift corrected doses were compared with results from the TPS. Comparison of peak doses to the urethra and rectum has been assessed against the proposed corrective protocol to limit overdosing these critical structures. An initial investigative level of 20% difference between measured and TPS peak dose was established, which corresponds to 1/3 of patients which was practical for the caseload. These patients were assessed resulting in corrective action being applied for one patient. Multiple triggering for selective investigative action is outlined. The use of a single in vivo measurement in the first fraction optimizes patient benefit at acceptable cost.
Subject Medical Physics
Keyword(s) brachytherapy
in vivo
dosimetry
HDR
prostate
investigative protocol
corrective action
TLD
urethral dosimetry
rectal dosimetry
DOI - identifier 10.1016/j.radonc.2008.08.016
Copyright notice © 2008 Elsevier Ireland Ltd. All rights reserved.
ISSN 0167-8140
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