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A novel composite porous coating approach for bioactive titanium-based orthopedic implants Qiu, D, Zhang, M and Grøndahl, L 2013, 'A novel composite porous coating approach for bioactive titanium-based orthopedic implants', Journal of Biomedical Materials Research. Part A, vol. 101A, no. 3, pp. 862-872. Document type: Journal Article Collection: Journal Articles Title A novel composite porous coating approach for bioactive titanium-based orthopedic implants Author(s) Qiu, D Zhang, M Grøndahl, L Year 2013 Journal name Journal of Biomedical Materials Research. Part A Volume number 101A Issue number 3 Start page 862 End page 872 Total pages 11 Publisher John Wiley and Sons Abstract Surface modification of titanium-based implants is considered a highly effective solution to enhance osseointegration. This study describes a novel Ti/hydroxyapatite (HA) composite porous coating produced using a cold spraying technique. Experimental results indicate desirable open-cell structure with 50-150 mu m pore size and 60-65% macroporosity. In particular, the reinforced HA particles are exposed to the surface of the coating resulting in enhanced mineralization ability in simulated body fluid. None of the coatings displayed a cytotoxic response in SaOS-2 cells cultured in vitro for up to 48 h. The bond strength between the porous coating and the Ti substrate was found to be 20 MPa. These properties are comparative to or better than products currently on the market and thus this novel coating has potential use in orthopedics. Subject Metals and Alloy Materials Keyword(s) Bioactivity Cold spraying Hydroxyapatite Porous coating Titanium implants DOI - identifier 10.1002/jbm.a.34372 Copyright notice © 2012 Wiley Periodicals ISSN 1549-3296 Related Links Link Description http://dx.doi.org/10.1002/jbm.a.34372 Link to Published Version   Versions Version Filter Type Wed, 06 May 2015, 09:38:55 EST Wed, 27 Jul 2016, 11:46:15 EST Wed, 30 Aug 2017, 14:20:56 EST Filtered Full Citation counts:   Cited 7 times in Thomson Reuters Web of Science Article | Citations Cited 4 times in Scopus Article | Citations Altmetric details: Access Statistics: 187 Abstract Views  -  Detailed Statistics Created: Wed, 06 May 2015, 08:28:00 EST by Catalyst Administrator