Broadband excitation and collection in fiber-optic nonlinear endomicroscopy

Ghimire, N, Bao, H and Gu, M 2013, 'Broadband excitation and collection in fiber-optic nonlinear endomicroscopy', Applied Physics Letters, vol. 103, no. 7, 073703, pp. 073703 -1-073703 -5.


Document type: Journal Article
Collection: Journal Articles

Title Broadband excitation and collection in fiber-optic nonlinear endomicroscopy
Author(s) Ghimire, N
Bao, H
Gu, M
Year 2013
Journal name Applied Physics Letters
Volume number 103
Issue number 7
Article Number 073703
Start page 073703 -1
End page 073703 -5
Total pages 5
Publisher A I P Publishing LLC
Abstract Broadband excitation and collection in a fiber-optic nonlinear endomicroscope are realized by using a single hollow-core double-clad photonic crystal fiber and a gradient index lens. Femtosecond pulses with central wavelengths in the range of 750-850 nm can be directly delivered through the core of the fiber for nonlinear excitation without pre-chirping. A gradient index lens with numerical aperture 0.8 designed to operate over the near-infrared wavelength range is used for focusing the laser beam from the fiber for nonlinear excitation and for collecting the fluorescent signal from the sample. This compact system is suitable to perform nonlinear imaging of multiple fluorophors in the wavelength range of 750-850 nm.
Subject Biomedical Engineering not elsewhere classified
Keyword(s) Broadband excitation
Central wavelength
Double-clad photonic crystals
Fluorescent signals
Gradient index lens
Near-infrared wavelength
Nonlinear excitation
Numerical aperture Engineering controlled terms: Electromagnetic pulse
Photonic crystal fibers
Wavelength
DOI - identifier 10.1063/1.4818750
Copyright notice © 2013 AIP Publishing LLC.
ISSN 0003-6951
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