Assessment of the biocompatibility of three-dimensional-printed polymers using multispecies toxicity tests

Zhu, F, Friedrich, T, Nugegoda, D, Kaslin, J and Wlodkowic, D 2015, 'Assessment of the biocompatibility of three-dimensional-printed polymers using multispecies toxicity tests', Biomicrofluidics, vol. 9, no. 6, 061103, pp. 1-5.


Document type: Journal Article
Collection: Journal Articles

Title Assessment of the biocompatibility of three-dimensional-printed polymers using multispecies toxicity tests
Author(s) Zhu, F
Friedrich, T
Nugegoda, D
Kaslin, J
Wlodkowic, D
Year 2015
Journal name Biomicrofluidics
Volume number 9
Issue number 6
Article Number 061103
Start page 1
End page 5
Total pages 5
Publisher American Institute of Physics Inc.
Abstract Additive manufacturing was adopted in multiple fields of life sciences. It is also becoming a popular tool for rapid prototyping of microfluidic and biomedical devices. Limited studies have been performed to investigate the biological implications of using 3D printed polymers. Here we assessed the biocompatibility of seven commercially available polymers, using a battery of standardized bioassays for chemical risk assessment. Our data show that leachates from photopolymers substrata appear to be very toxic to vertebrates and several invertebrate indicator organisms. These results demonstrate significant consequences for the use of selected photopolymers in the fabrication of bio-devices.
Subject Analytical Chemistry not elsewhere classified
Keyword(s) Biocompatibility
Photopolymers
Risk assessment Bio-devices
Biological implications
Biomedical devices
Chemical risk assessment
Indicator organisms
Life-sciences
Multi-species
Toxicity test
DOI - identifier 10.1063/1.4939031
Copyright notice © 2015 AIP Publishing LLC
ISSN 1932-1058
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Citation counts: TR Web of Science Citation Count  Cited 16 times in Thomson Reuters Web of Science Article | Citations
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