Anodization parameters influencing the morphology and electrical properties of TiO2 nanotubes for living cell interfacing and investigations

Khudhair, D, Bhatti, A, Li, Y, Hamedani, H, Garmestani, H, Hodgson, P and Nahavandi, S 2016, 'Anodization parameters influencing the morphology and electrical properties of TiO2 nanotubes for living cell interfacing and investigations', Materials Science and Engineering C, vol. 59, pp. 1125-1142.


Document type: Journal Article
Collection: Journal Articles

Title Anodization parameters influencing the morphology and electrical properties of TiO2 nanotubes for living cell interfacing and investigations
Author(s) Khudhair, D
Bhatti, A
Li, Y
Hamedani, H
Garmestani, H
Hodgson, P
Nahavandi, S
Year 2016
Journal name Materials Science and Engineering C
Volume number 59
Start page 1125
End page 1142
Total pages 18
Publisher Elsevier Ltd
Abstract Nanotube structures have attracted tremendous attention in recent years in many applications. Among such nanotube structures, titania nanotubes (TiO2) have received paramount attention in the medical domain due to their unique properties, represented by high corrosion resistance, good mechanical properties, high specific surface area, as well as great cell proliferation, adhesion and mineralization. Although lot of research has been reported in developing optimized titanium nanotube structures for different medical applications, however there is a lack of unified literature source that could provide information about the key parameters and experimental conditions required to develop such optimized structure. This paper addresses this gap, by focussing on the fabrication of TiO2 nanotubes through anodization process on both pure titanium and titanium alloys substrates to exploit the biocompatibility and electrical conductivity aspects, critical factors for many medical applications from implants to in-vivo and in-vitro living cell studies. It is shown that the morphology of TiO2 directly impacts the biocompatibility aspects of the titanium in terms of cell proliferation, adhesion and mineralization. Similarly, TiO2 nanotube wall thickness of 30-40 nm has shown to exhibit improved electrical behaviour, a critical factor in brain mapping and behaviour investigations if such nanotubes are employed as micro-nano-electrodes.
Subject Biomedical Engineering not elsewhere classified
Keyword(s) Anodization
TiO2
Titania nanotubes
DOI - identifier 10.1016/j.msec.2015.10.042
Copyright notice © 2015 Elsevier B.V.
ISSN 1873-0191
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