Aortic augmentation index in endurance athletes: a role for cardiorespiratory fitness

Denham, J, Brown, N, Tomaszewski, M, Williams, B, O'Brien, B and Charchar, F 2016, 'Aortic augmentation index in endurance athletes: a role for cardiorespiratory fitness', European Journal of Applied Physiology, vol. 116, no. 8, pp. 1537-1544.

Document type: Journal Article
Collection: Journal Articles

Title Aortic augmentation index in endurance athletes: a role for cardiorespiratory fitness
Author(s) Denham, J
Brown, N
Tomaszewski, M
Williams, B
O'Brien, B
Charchar, F
Year 2016
Journal name European Journal of Applied Physiology
Volume number 116
Issue number 8
Start page 1537
End page 1544
Total pages 8
Publisher Springer
Abstract Endurance exercise improves cardiovascular health and reduces mortality risk. Augmentation index (AIx) reflects adverse loading exerted on the heart and large arteries and predicts future cardiovascular disease. The purpose of this study was to establish whether endurance athletes possess lower AIx and aortic blood pressure compared to healthy controls, and to determine the association between AIx and cardiorespiratory fitness. Forty-six endurance athletes and 43 healthy controls underwent central BP and AIx measurements by non-invasive applanation tonometry before a maximal exercise test. Peak oxygen uptake () was assessed by pulmonary analysis. Relative to controls, athletes had significantly lower brachial diastolic blood pressure (BP, -4.8 mmHg, p < 0.01), central systolic BP (-3.5 mmHg, p = 0.07), and AIx at a heart rate of 75 beats min(-1) (AIx@75, -11.9 %, p < 0.001). No AIx@75 differences were observed between athletes and controls when adjusted for age and [athletes vs controls mean (%) +/- SE: -6.9 +/- 2.2 vs -5.7 +/- 2.3, p = 0.76]. Relative to men with low , those with moderate and high had lower age-adjusted AIx@75 (p < 0.001). In women, those with high had lower AIx@75 than those with low and moderate (p < 0.01). The lower AIx@75 in endurance athletes is partly mediated by . While an inverse relationship between AIx@75 and was found in men, women with the highest possessed lowest AIx@75 compared to females with moderate or poor cardiorespiratory fitness. We recommend aerobic training aimed at achieving a minimum of 45 ml kg(-1) min(-1) to decrease the risk of future cardiovascular events and all-cause mortality.
Subject Sports Medicine
Keyword(s) Arterial stiffness
Cardiovascular health
Central blood pressure
VO 2max
DOI - identifier 10.1007/s00421-016-3407-x
Copyright notice © Springer-Verlag Berlin Heidelberg 2016
ISSN 1439-6319
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