A pilot evaluation of a computer-based psychometric test battery designed to detect impairment in patients with cirrhosis

Cook, N, Kim, J, Pasha, Y, Crossey, M, Schembri, A, Harel, B, Kimhofer, T and Taylor-Robinson, S 2017, 'A pilot evaluation of a computer-based psychometric test battery designed to detect impairment in patients with cirrhosis', International Journal of General Medicine, vol. 10, pp. 281-289.


Document type: Journal Article
Collection: Journal Articles

Title A pilot evaluation of a computer-based psychometric test battery designed to detect impairment in patients with cirrhosis
Author(s) Cook, N
Kim, J
Pasha, Y
Crossey, M
Schembri, A
Harel, B
Kimhofer, T
Taylor-Robinson, S
Year 2017
Journal name International Journal of General Medicine
Volume number 10
Start page 281
End page 289
Total pages 9
Publisher Dove Medical Press
Abstract Background: Psychometric testing is used to identify patients with cirrhosis who have developed hepatic encephalopathy (HE). Most batteries consist of a series of paper-and-pencil tests, which are cumbersome for most clinicians. A modern, easy-to-use, computer-based battery would be a helpful clinical tool, given that in its minimal form, HE has an impact on both patients quality of life and the ability to drive and operate machinery (with societal consequences). Aim: We compared the Cogstate computer battery testing with the Psychometric Hepatic Encephalopathy Score (PHES) tests, with a view to simplify the diagnosis. Methods: This was a prospective study of 27 patients with histologically proven cirrhosis. An analysis of psychometric testing was performed using accuracy of task performance and speed of completion as primary variables to create a correlation matrix. A stepwise linear regression analysis was performed with backward elimination, using analysis of variance. Results: Strong correlations were found between the international shopping list, international shopping list delayed recall of Cogstate and the PHES digit symbol test. The Shopping List Tasks were the only tasks that consistently had P values of <0.05 in the linear regression analysis. Conclusion: Subtests of the Cogstate battery correlated very strongly with the digit symbol component of PHES in discriminating severity of HE. These findings would indicate that components of the current PHES battery with the international shopping list tasks of Cogstate would be discriminant and have the potential to be used easily in clinical practice.
Subject Clinical Sciences not elsewhere classified
Keyword(s) Cirrhosis
Cogstate
Hepatic encephalopathy
Minimal hepatic encephalopathy
Psychometric hepatic encephalopathy score
Psychometric testing
DOI - identifier 10.2147/IJGM.S140197
Copyright notice © 2017 Cook et al. This work is published by Dove Medical Press Limited, and licensed under a Creative Commons Attribution License. The full terms of the License are available at http://creativecommons.org/licenses/by/4.0/.
ISSN 1178-7074
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