Brown fat uptake of F-18-FDG on dual time point PET/CT imaging

Abdul Razak, H, Noraini, A, Rossetti, C and Nordin, A 2010, 'Brown fat uptake of F-18-FDG on dual time point PET/CT imaging', Singapore Medical Journal, vol. 51, no. 2, pp. 37-39.


Document type: Journal Article
Collection: Journal Articles

Title Brown fat uptake of F-18-FDG on dual time point PET/CT imaging
Author(s) Abdul Razak, H
Noraini, A
Rossetti, C
Nordin, A
Year 2010
Journal name Singapore Medical Journal
Volume number 51
Issue number 2
Start page 37
End page 39
Total pages 3
Publisher Singapore Medical Association
Abstract The aim of this report was to assess the changes in the 18F-fluorodeoxyglucose (18F-FDG) uptake of brown fats on integrated positron emission tomography/computed tomography (PET/ CT) imaging. The patient presented with an enlargement of the neck lymph nodes, and was suspicious for tuberculous lymphadenitis. A whole body PET/CT imaging was performed, followed by a delayed imaging of the neck and thoracic regions. A visually increased 18F-FDG uptake was taken as a positive finding. A semi-quantitative evaluation was performed using a maximum standardised uptake value (SUVmax) with a cut-off value above 2.5. There were a number of 18F-FDG avid activity areas seen at the supraclavicular, mediastinal, paravertebral and perirenal regions. These are in keeping with the physiological 18F-FDG uptake in brown fat. The differences in SUVmax between the two scans ranged from -20 percent to +20 percent. Based on our observation, dual time point imaging may not be a reliable method for assessing the 18F-FDG uptake of brown fat.
Keyword(s) 18F-FDG
brown fat
dual time point imaging
PET/CT
Copyright notice © Copyright 2010 Elsevier B.V
ISSN 0037-5675
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